Phentermine is voted to be the most popular and most effective weight loss drug in the United States, so much that it is the most common weight loss drug prescribed to cases of serious obesity and overweight . Phentermine and Topamax are two very different types of medications. Topiramate is available in tablet and capsule form (25 mg, 50 mg, 100 mg, and 200 mg). I take 225mg of Effexor and have gained 30 pounds. Phentermine and topiramate extended-release (long-acting) capsules are used to help adults who are obese or who are overweight and have weight-related medical problems to lose weight and to keep from gaining back that weight. I started taking Topamax about 5 weeks ago for migraines and its been working like a charm. It's well worth a try for you to ask about getting them. 3 Likes. The "dopiness" is not a myth, that was terrible. Although Topamax (topiramate) has helped many patients, it is by no means the silver bullet to stop migraine. Here is the low down on it. Topiramate Dosage for Weight Loss. ! However, I did experience many other side effects. I stopped gaining weight but haven’t really lost any yet. It is an appetite suppressor and an energy booster. I guess my body got used to it and it stopped working. It’s popularity has also been hampered by the side effects that some patients experience.. Of course there are many good alternatives to Topamax, but researchers are looking for something similar that will work for patients that are good candidates for something like topiramate, … Any feedback would be greatly appreciated. My dr gave me 25mg x 2 of Topamax for weight management. I was able to handle things with a few glasses of wine on the Effexor but I’m really worried about light social drinking on Topamax. They were approved for migraines by the FDA in October 2010. Phentermine and topiramate extended-release capsules must be used along with a reduced calorie diet and exercise plan. I don’t take it anymore because it made me feel like I need to pull my skin off. I was also very depressed. You can start with a low dose of 25 or 50 mg per day, twice a day with or without food. 2 Likes. Very unusual for them to stop working as well. After some time the drug stopped working on its own and she decided to combine it with 50mg of Topiramate (a 25mg dose 2 x’s a day) then after about 20 more lbs of weight loss and a plateau the full dose of 100mg (50mg pills 2x’s a day). Nigel Topamax is not a "speed" drug at all, my Dr. gives it to many patients for weight loss. The injections have greatly helped me, (until they just stopped working as well after getting them for 2 years). Phentermine is intended to be used as a weight loss aid, while Topamax is intended to be used to treat certain seizure disorders or prevent migraines from occurring. Usual dosage for migraines is around 50mg, at this dosage you will have some loss of appetite but not for long. For weight loss it takes 100mg to 125 mg, It worked for me very well, but yes the side effects can be annoying. Phentermine is only available with a doctor’s prescription. I’m still hoping. I havent had one migraine or headache in weeks!! The injections can work for up to 3 months or longer. I have some minor side effects including dry mouth, itchiness, and weight loss, but other than that, its great. I was on topomax about 4 years ago (not for weight loss). I’m on topamax for weight loss, but I don’t think it does anything for me. Both medications, however, may cause weight loss. I did lose a lot of weight while on it, about probably 20-30 lbs over two or three months. The truth is this drug is not for weight loss, but an individual may experience weight loss as a … Injections have greatly helped me, ( until they just stopped working bullet to stop migraine i havent one... 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